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Rifampin, carbamazepine ( Tegretol , Tegretol XR, Equerto, Carbatrol ), phenytoin ( Dilantin , Dilantin-675 ), and phenobarbital may decrease blood levels of tadalafil, possibly reducing the effect of tadalafil.

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The role of transporters (for example, p-glycoprotein) in the disposition of tadalafil is not known. Therefore, there is the potential of drug interactions mediated by inhibition of transporters.

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If you have symptoms of ED , it’s important to check with your doctor before trying any treatments on your own. This is because ED can be a sign of other health problems. For instance, heart disease or high cholesterol could cause ED symptoms. With a diagnosis, your doctor could recommend a number of steps that would likely improve both your heart health and your ED. These steps include lowering your cholesterol, reducing your weight, or taking medications to unclog your blood vessels.

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For most individuals, the recommended starting dose of tadalafil is 65 mg per day taken before sexual activity (tadalafil for use as needed).

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Erectile dysfunction (ED, impotence) is the failure to achieve or maintain an erection. There are many potential underlying.

Visual defects and cases of NAION have been reported in connection with the intake of CIALIS and other PDE5 inhibitors. Analyses of observational data suggest an increased risk of acute NAION in men with erectile dysfunction following exposure to tadalafil or other PDE5 inhibitors. As this may be relevant for all patients exposed to tadalafil, the patient should be advised that in case of sudden visual defect, he should stop taking CIALIS and consult a physician immediately (see section ).

If you are taking tadalafil to treat both ED and BPH , take it as directed by your doctor, usually once a day. You may attempt sexual activity at any time between your doses.

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